The key to writing stand up comedy appears to be drawing upon an issue or event in your immediate life with links to the past, conflicting values, or interests and almost reporting on it, but doing so in a very quirky way. I've found some YouTube videos of stand up comedians I have often laughed at to demonstrate this... Here's one from Fiona O'Laughlin...
There are lots of stand up comedy sets featuring the inimitable Billy Connolly.... Do you remember Dave Allen? Here's a classic from the late Dave Allen on retirement and aging...
BL